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The biggest concern is that the tissue dried out overnight when you didn't notice it. This can lead to necrosis and the tissue will have to be removed. If the tissue is in fact viable then it can be replaced and the animal should recover. When my female prolapsed (a small one) I immediately put her in some very shallow water with a sugar paste. Preparation H can also be used to help shrink the tissues safely. My snake's prolapse reduced on it's own but as soon as she perched at the vets, she reprolapsed. The vet ended up putting two stiches on each side of the cloaca to hold the tissue in. If the tissue on your snake goes back, you can use a fabric bandaid and cover the cloaca to hold the tissue in. Let the bandaid come off on it's own. If necessary I would replace the bandaid. The nice thing about the stiches was that any fecal matter or urates were able to pass and I soaked her daily. I've heard of people using the blunt end of a sexing probe to push the prolapse back in. I wasn't confident enough to do it..plus I was freaking out. She was my favorite animal. I still don't think I'd replace a prolapse unless it's very small or I have no other choice. I'd leave the animal without a perch if possible for a couple of weeks at least. I waited a full month before offering the first food item...a very small mouse. Then I waited 2 weeks and offered another small mouse. I soaked her every few days during this time and had the stiches removed after 2 weeks. After the second feeding I waited another 2 weeks and then offered her a normal sized food item. Then I waited some more. She's never had an issue since, but I am extremely conservative with feeding now. I only feed my snakes every 2-3 weeks and then it's an item the animals size and not much larger. She's gone almost 3 years since the prolapse and I will be breeding her for the first time this year.